Challenges and support for children of parents with mental health and substance use disorders: a scoping review
Review Article

Challenges and support for children of parents with mental health and substance use disorders: a scoping review

Kim Jørgensen1,2 ORCID logo, Jesper Frederiksen3,4 ORCID logo, Morten Hansen5, Martina Dubovcová6 ORCID logo

1Department of People and Technology, Roskilde University, Roskilde, Denmark; 2Department of Nursing and Health Promotion, Faculty of Health Sciences, Oslo Metropolitan University, Oslo, Norway; 3Medical Department, Zealand University Hospital, Roskilde, Denmark; 4Department of Regional Health Research, University of Southern Denmark, Odense, Denmark; 5Bostedsteamet, Ishøj, Kobenhavn Ø, Denmark; 6Jessenius Faculty of Medicine, Clinic of Psychiatry of University Hospital, Martin, Slovakia

Contributions: (I) Conception and design: J Frederiksen; (II) Administrative support: None; (III) Provision of study materials or patients: K Jørgensen; (IV) Collection and assembly of data: All authors; (V) Data analysis and interpretation: All authors; (VI) Manuscript writing: All authors; (VII) Final approval of manuscript: All authors.

Correspondence to: Kim Jørgensen, PhD, MSc, RN. Department of People and Technology, Roskilde University, Universitetsvej 1, Postbox 260, 4000 Roskilde, Denmark; Department of Nursing and Health Promotion, Faculty of Health Sciences, Oslo Metropolitan University, Pilestredet Park 0890, 0176 Oslo, Norway. Email: kimjo@ruc.dk.

Background: Children of parents with mental health and substance use disorders face significant emotional, psychological, and developmental challenges. While research has recognized the need for support, interventions often fail to address children’s specific developmental needs or provide holistic, integrated care models. This scoping review identifies key challenges and effective support mechanisms to inform future interventions.

Methods: A scoping review was conducted following Arksey and O’Malley’s framework. Systematic searches were performed in CINAHL, PubMed, Scopus, and Web of Science [2014–2024]. Studies examining the experiences, risks, and support mechanisms for children aged 10–18 living with parents experiencing mental health and substance use disorders were included. Thematic analysis was applied to identify patterns in resilience-building interventions and integrated support approaches.

Results: Findings highlight four key themes: (I) impact and risk factors children experience increased emotional distress, developmental delays, and social isolation, exacerbated by stigma and inadequate systemic support; (II) parent and family engagement interventions incorporating parents and extended family members (e.g., grandparents) improve family stability and child resilience; (III) integrated support systems—cross-sector collaboration between healthcare, education, and social services is essential for effective intervention; (IV) continuous monitoring and adaptive support—ongoing, developmentally appropriate interventions tailored to individual needs improve long-term outcomes.

Conclusions: Policymakers and practitioners must prioritize integrated, evidence-based interventions to mitigate risks and improve the well-being of children of parents with mental health and substance use disorders. Future research should focus on long-term intervention effectiveness and adaptive strategies for evolving needs.

Keywords: Substance use; resilience; children of parents with mental health disorders; integrated support systems; family engagement


Received: 02 November 2024; Accepted: 24 February 2025; Published online: 16 May 2025.

doi: 10.21037/jhmhp-24-131


Highlight box

Key findings

• Children of parents with mental health and substance use disorders are at heightened risk for emotional, psychological, and developmental challenges.

• Integrated and multi-level support systems are vital in mitigating these risks, with a focus on resilience-building interventions and consistent family engagement.

What is known and what is new?

• Children of parents with mental health and substance use disorders face significant emotional and developmental challenges due to unstable caregiving environments, trauma, and inconsistent care. The need for integrated, multi-level support systems is well recognized.

• This study emphasizes the importance of adaptive support tailored to children’s developmental stages. It also highlights the stabilizing role of extended family members, such as grandparents, and identifies stigma reduction and integrated care models as key to promoting timely interventions.

What is the implication, and what should change now?

• Policymakers must prioritize funding for integrated care models that bridge healthcare, social services, and education. Practitioners need to adopt culturally sensitive, trauma-informed approaches when supporting families. Community organizations and schools should collaborate to create accessible and tailored support systems for children.

• Initiatives to reduce stigma surrounding parental mental health and substance use disorders, and the development of family-centered, evidence-based intervention programs should be prioritized. Continuous monitoring and evolving support mechanisms are necessary to address children’s evolving developmental needs.


Introduction

Children whose parents experience mental health disorders and substance use challenges represent a highly vulnerable population, as they often contend with unstable home environments, inconsistent caregiving, and an elevated risk of exposure to traumatic events such as neglect or abuse (1). Stigma and secrecy surrounding parental mental illness can further isolate these children, limiting their access to supportive social networks (2). Compounding these risks, the prevalence of mental health disorders among youth has been on the rise globally. In Norway, for instance, diagnoses in boys climbed from 7.6% to 10.9% and in girls from 7.3% to 12.5% between 2010 and 2022, underscoring the urgency of addressing the needs of children impacted by parental mental illness and substance use (3).

Despite clear evidence of the challenges these children face, specialized interventions remain scarce (2). Existing services often focus on treating the parent or the family unit as a whole, overlooking children’s individual experiences and developmental stages (4). To address these gaps, resilience has emerged as a core concept, highlighting protective factors like emotional regulation, coping strategies, and social skills that can mitigate adverse circumstances (5-7). However, many resilience-building programs are too generalized, insufficiently tailored to the unique experiences of these children, or fail to consider gender differences that significantly influence how boys and girls respond to parental mental illness and substance use (4).

Further complicating the situation is the critical developmental window of ages 10–18 years, during which children experience pronounced physical, emotional, and cognitive changes (8,9). Early adolescence is both a period of heightened vulnerability and an opportune time to introduce targeted, evidence-based interventions that can establish healthier coping mechanisms. Research consistently shows that proactive support can prevent the progression of mental health disorders and alleviate long-term burdens on healthcare systems (10-12). However, a lack of straightforward, widely accessible programs, alongside limited qualitative research on children’s lived experiences, continues to impede the development of effective, culturally sensitive interventions. This study therefore aims to fill these gaps by identifying current best practices and proposing a streamlined, practical intervention to bolster emotional regulation, coping strategies, and social skills in children affected by parental mental health and substance use disorders. To ensure real-world applicability, we will spotlight tangible, existing programs (including parent-focused, child-focused, and school or community-based interventions) and detail them in a user-friendly format. We will also outline a policy framework that goes beyond calls for increased funding, advocating instead for multifaceted approaches such as stigma reduction campaigns, workforce training, and interdisciplinary collaboration that can more holistically support this at-risk youth population.

By systematically examining evidence from these diverse viewpoints in a comprehensive manner, we aim to provide valuable insights for policymakers, mental health practitioners, and researchers. We present this article in accordance with the PRISMA-ScR reporting checklist (available at https://jhmhp.amegroups.com/article/view/10.21037/jhmhp-24-131/rc).


Methods

The methodology employed in this study is a scoping review, designed to thoroughly explore existing literature on the perspectives of children, parents, and healthcare professionals regarding family participation in mental health care. These insights will aid in developing family-centered care models that are evidence-based and deeply respectful of family autonomy and empowerment.

Our scoping review adheres to principles akin to those of systematic reviews, emphasizing rigorous and transparent methods at every stage. By meticulously documenting our processes, we enable replication by other researchers, thereby enhancing the reliability of our findings and addressing concerns about methodological rigor (13). The scoping review method seeks to achieve both depth and breadth, aiming to thoroughly understand how the subject is addressed in the current literature. As we become more familiar with the literature, we may refine our search terms and conduct more sensitive searches to ensure comprehensive coverage. This flexible approach allows for an iterative and reflective process throughout the study. In light of these distinctions, we will now detail the six stages of the framework we employed for our scoping study (13).

Stage 1: identifying the working questions

Regarding the aim of the scoping review, two working questions were developed to guide the following inquiry

The question in step one aims to clarify the overarching focus of the review and establish a clear boundary for what will be examined. By defining the core issue early on, it ensures all subsequent steps are aligned with the central objective, guiding both the inclusion criteria and analytical direction of the study.

  • What characterizes the range and nature of the existing scientific literature on the challenges faced by children of parents with mental health and substance use disorders, and the support available to them?
  • What are the key themes and findings regarding the challenges these children face and the support mechanisms that effectively assist them, as reported in the literature?

Stage 2: identifying relevant studies

From May 2024 to November 2024, we conducted systematic online searches across four databases relevant to mental health nursing and qualitative, peer-reviewed literature: CINAHL, PubMed, Scopus, and Web of Science. Our initial systematic search was structured into four distinct blocks, each focusing on:

  • Block A: children of parents with mental health disorders;
  • Block B: children of parents with substance use disorders;
  • Block C: challenges and risks encountered by these children;
  • Block D: support interventions and resilience-building programs.

For each block, we used a combination of controlled vocabulary from database thesauri and free-text terms to capture relevant literature comprehensively. A comprehensive search strategy, including MeSH terms, Boolean operators, search limits, and databases used, is detailed in the sought strategy to ensure transparency and reproducibility.

During the search process, adjustments were made as follows:

  • Block A was broadened to include a wider range of parental mental health disorders, such as depression, anxiety, bipolar disorder, and schizophrenia, as well as substance-related issues like alcohol and drug misuse and co-occurring disorders.
  • Block B was refined to encompass perspectives from children aged 10–18 years, their parents, and healthcare professionals, with a focus on emotional and psychological impacts, developmental challenges, social isolation, trauma exposure, and gender-specific responses experienced by these children.
  • Block C was extended to include a comprehensive array of challenges and risks specific to these children, emphasizing the effects of family dynamics, social and environmental factors, and systemic barriers to support.
  • Block D was refined to cover a diverse range of support interventions, including structured resilience-building programs, therapeutic approaches like counseling and cognitive-behavioral therapy, informal support mechanisms such as peer groups and community initiatives, and programs aimed at enhancing coping skills and emotional regulation among affected children.

The search was carried out in collaboration with a research librarian and was completed in November 2024. All identified references were imported and managed using Covidence software.

To ensure a thorough approach, we adopted broad definitions for key concepts related to the challenges faced by these children and the available support. Keywords such as ‘resilience’, ‘coping strategies’, ‘emotional regulation’, ‘social skills’, ‘interventions’, ‘support programs’, ‘psychosocial support’, ‘preventive measures’, ‘children of parents with mental illness’, ‘parental substance use’, ‘adolescent mental health’, and ‘family interventions’ were included to maximize retrieval of all pertinent literature on the topic. We anticipated that broad definitions could result in an extensive number of references. To manage this, we maintained a wide scope initially, allowing us to refine and effectively address the literature’s volume and scope as the project evolved. To ensure accessibility and facilitate the comparability of findings within the global research community, we limited the search to articles published in English. This decision ensures that the included studies can be widely understood and incorporated into international discussions, which is crucial for developing universally applicable recommendations.

To ensure the relevance of our findings to current practices and policy discussions, we limited our review to articles published in the last ten years [2014–2024]. This time frame reflects the most recent advances in research and practice, capturing evolving understandings of the challenges and support mechanisms for children of parents with mental health and substance use disorders. By focusing on recent literature, we ensure that the findings and recommendations are aligned with contemporary frameworks, interventions, and socio-political contexts (12).

Stage 3: study selection

To ensure consistent decision-making, we established inclusion and exclusion criteria similar to those used in systematic reviews (14). Our inclusion criteria focused on peer-reviewed, full-text journal articles published from 2014 to 2024. We specifically sought studies that explored the experiences of children aged 10–18 years, their parents, and healthcare professionals within the contexts of mental health and substance use disorders. We included both qualitative and quantitative research that addressed the challenges faced by these children and the interventions designed to support them. Additionally, our criteria were refined to include studies that examined resilience, coping strategies, emotional regulation, social skills, and responses specific to gender. These additions provided insights into effective support mechanisms. We excluded conference abstracts, book chapters, dissertations, or any non-peer-reviewed materials. Studies were also excluded if they did not focus on mental health and substance use challenges affecting if the target age range was not clearly analyzable, or if they did not examine relevant outcomes. From an initial 4,233 references, we removed 114 duplicates, leaving 4,119 for review. After title and abstract screening, 3,892 references were excluded, followed by 208 more based on specific criteria (Figure 1). This process led to a final selection of 19 studies that met our criteria and contributed to the review’s objectives.

Figure 1 PRISMA—challenges and support for children of parents.

Stage 4: charting the data

Data charting involved extracting information to describe the range and nature of the included studies (Table 1). Additionally, the charting process entailed a structured approach to data analysis, starting with a broad comprehension of the data, followed by identifying relevant statements, finding commonalities, and ultimately discerning central themes related to the challenges faced by these children and the support mechanisms that assist them (15,16). This process was facilitated by team discussions and the use of Covidence software.

  • Overall understanding: reviewing the studies to develop a comprehensive understanding of the data.
  • Meaning unit identification: identifying and extracting “meaning units” statements relevant to the research aim.
  • Commonality identification: analyzing the meaning units to identify common meanings, which were then grouped into descriptive categories.
  • Theme identification: conducting an analysis to identify patterns of regularities and variations, leading to the identification of central themes emerging from the data. Steps three and four were conducted through discussions within the research team (15).

Table 1

Selected articles

Author(s); year of publication; study location Title Study populations Aims of the study Methodology Service user or/and health professional perspective Important results
Barrett S, Smart D, Bate A, et al.; 2024; North East England, UK Exploring caregiver perspectives in the context of parental substance use: A qualitative study Nineteen caregivers (including mothers, fathers, grandparents, aunts, uncles, and siblings aged 25–65+ years) of dependent children (aged 4–17 years) from families affected by parental substance use participated To examine the experiences and support needs of caregivers affected by another parent’s substance use Qualitative, in-depth interviews with thematic analysis Caregiver perspective on the challenges of balancing caregiving and personal needs in the context of substance use The findings highlighted caregivers’ perspectives on the challenges of balancing caregiving responsibilities with personal needs in the context of substance use. Caregivers experienced cumulative stress in their roles, often feeling their needs were unrecognized by support services. Moreover, interactions with statutory services frequently exacerbated their stress. There is a clear need for resources to help caregivers talk to children about substance use and to provide appropriate support for caregivers and families
Champion KE, Hunter E, Gardner LA, et al.; 2023; Australia Parental Information Needs and Intervention Preferences for Preventing Multiple Lifestyle Risk Behaviors Among Adolescents Parents of children aged 11–18 years residing in Australia To assess parents’ knowledge about adolescent risk behaviors, barriers to engaging in healthy behaviors, and preferences for a parent-based prevention intervention Cross-sectional web-based survey conducted between June 2022 to August 2022 Parent perspective Most parents lacked knowledge about adolescent health guidelines, specifically physical activity, screen time, and diet. Parents preferred a web based, brief intervention with features like goalsetting and motivational interviewing. The findings inform the development of future parent based preventive interventions
Dyba J, Moesgen D, Klein M, et al.; 2019; Germany Mothers and fathers in treatment for methamphetamine addiction—Parenting, parental stress, and children at risk 87 parents (68 mothers and 19 fathers) with methamphetamine addiction in recovery To analyze parenting practices and parental stress, as well as children’s behavioral problems among parents in treatment for methamphetamine addiction Design: cross-sectional study The study is based on self-reported data from methamphetamine addicted parents, focusing on their experiences and perceptions Parents recovering from methamphetamine addiction experience high parental stress and dysfunctional parenting (laxness and over reactivity), which lead to behavioral problems in their children. Parental stress predicts children’s issues beyond the effects of substance use. The study emphasizes the need for family-oriented interventions to enhance parenting skills and prevent problems in children
Participants were recruited from seven outpatient substance abuse treatment facilities and five child welfare institutions Data collection: parents completed paper-and-pencil questionnaires in group settings within treatment facilities
Eiden RD, Godleski SA, Colder CR, et al.; 2020; Buffalo, New York, USA Early Childhood Risk and Protective Factors Predicting Resilience against Adolescent Substance Use 227 families recruited when children were 12 months old To examine associations between early childhood risk and protective factors and resilience against adolescent substance use Longitudinal, prospective study Perspective: research and clinical perspective focusing on early intervention and prevention Troubled children had lower early emotion regulation and effortful control
Included alcoholic and nonalcoholic families To define resilience as low or no substance use in the context of having a parent with alcohol problems Assessments at child ages 12, 18, 24, 36 months, and 15–17 years Relevant for health professionals involved in child development, psychology, and substance use prevention Resilient children were more reactive to novelty
Followed until children were 15–17 years old (n=182 at final follow-up) To identify early predictors of resilience or vulnerability among adolescents Measures: child temperament and self-regulation Parents of resilient children had milder alcohol symptoms; fathers were less aggravated
Parent psychopathology (antisocial behavior, depression), alcohol use Parental alcohol severity was linked to adolescent substance use
Family relationships (partner conflict, parent child interactions) Early childhood functioning and family factors are key for adolescent resilience
Analysis: multivariate analyses (MANOVAs) to examine group differences Passive gene-environment correlations may explain these associations
Guastaferro K, Osborne MC, Lai BS, et al.; 2021; Metro Atlanta, Georgia, USA Parent and Child Reports of Parenting Behaviors: Agreement Among a Longitudinal Study of Drug Court Participants 50 parent child dyads Examine the agreement between parent and child reports of parenting behaviors Longitudinal cohort study: data collected at baseline (Time 1) and one year later (Time 2) Service user perspective: focused on self-reports from parents enrolled in drug courts and their children Agreement between parent and child reports of parenting behaviors was slight to fair
Parents enrolled in adult drug courts Describe the association between agreement and child MH outcomes Parents and children completed assessments including: Alabama Parenting Questionnaire; Behavior Assessment System for Children; Brief Symptom Inventory Parents rated their parenting behaviors more positively than their children did
Children aged 8–18 years Discrepancies were observed in areas of involvement, positive parenting, monitoring, inconsistent discipline, and corporal punishment
Parents predominantly male (58%), White (60%), mean age 38.2 years Statistical analyses included weighted kappa and multivariable linear regression models When parents rated their parenting more positively than children did, it was associated with negative effects on child self-esteem and personal adjustment
Children average age 11.49 years, predominantly male (52%) Findings highlight the importance of obtaining both parent and child reports to identify children at higher risk for negative outcomes and to improve assessment within drug court systems
Huckle T, Romeo JS; 2023; New Zealand Estimating child maltreatment cases that could be alcohol-attributable in New Zealand 58,359 children aged 0–17 years and their parents To compare the risk of child maltreatment among children exposed versus not exposed to parents with an alcohol-attributable hospitalization or MH/addiction service use Cohort study using data from the Statistics New Zealand Integrated Data Infrastructure (IDI): The study analyzes existing administrative and health records Children exposed to parents with alcohol-attributable hospitalization or MH/addiction service use had a 65.1% increased risk of substantiated child maltreatment
Participants were from New Zealand, using data from national databases To estimate the cases of child maltreatment that could be attributable to alcohol under two different conditions in New Zealand Survival analysis based on a Bayesian piecewise exponential model Does not involve direct input from service users or health professionals In 2017, an estimated 14.6% of documented child maltreatment cases could be attributable to parents with severe alcohol use
Adjusted for potential confounders Provides a population-level perspective on the issue An estimated 11.4% of child maltreatment cases could be attributable to hazardous parental drinking
Sensitivity analyses using New Zealand Health Survey 2017 data Highlights the need for alcohol policy interventions to reduce severe or hazardous drinking among parents to prevent child maltreatment
Lees B, Stapinski LA, Teesson M, et al.; 2021; USA Problems experienced by children from families with histories of substance misuse: An ABCD Study Participants: 11,873 children (52.1% male) Provide a comprehensive assessment of problems experienced by substance-naïve children with positive family histories of substance misuse Design: cross-sectional analysis using baseline data from the ABCD Study® Service user perspective: focused on the experiences and outcomes of children from families with histories of substance misuse Children aged 9–10 years with family substance misuse histories show thinner cortices, larger frontal and occipital brain areas, and higher rates of psychopathology and sleep disturbances, including disorders like anxiety and PTSD. These issues worsen with more extensive family history. No differences were found in cognition or impulsivity. Negative correlations exist between psychopathology and neural measures. Early prevention targeting these vulnerabilities is recommended
Age range: 9.0–10.9 years (mean age 9.9 years) To examine neurobiological, cognitive, behavioral, and psychological outcomes associated with family history of substance misuse Data collection: parent and child reports, neuroimaging data
Key groups: family history positive (FHP): 26.3% (children with ≥1 parent or ≥2 grandparents with substance misuse history); family history negative (FHN): children with no such family history To assess how the density of family history affects these outcomes Statistical analysis: mixed models to test associations between family history and outcomes, controlling for confounding factors (e.g., sociodemographic, prenatal exposures, family history of psychopathology)
Characteristics: substance-naïve youth (had not consumed a full drink of alcohol or tried other substances)
Lopes AI, Leal J, Sani AI; 2021; Portugal Parental Mental Health Problems and the Risk of Child Maltreatment: The Potential Role of Psychotherapy Focus on families with parental MH problems, especially children at risk of maltreatment due to parental psychopathology The study aims to provide a theoretical review on the risks children face in families where parents suffer from MH issues and to discuss how psychotherapy, specifically EFT, can reduce the risk of child maltreatment This is a theoretical review based on international empirical studies over the past two decades, focusing on parental MH and its effects on child maltreatment risk The study emphasizes both service user and health professional perspectives, addressing how psychotherapy can help parents with MH issues and protect their children from maltreatment The study highlights the importance of psychotherapy in addressing emotional and interpersonal problems in parents with MH disorders. It suggests that EFT is a promising intervention for reducing aggressive behaviors and child maltreatment by improving family dynamics and parenting skills
Maina G, Ogenchuk M, Gaudet S; 2021; Saskatoon, Canada Living with parents with problematic substance use: Impacts and turning points 2 individuals who grew up with parents having substance use problems To explore the experiences and impacts on individuals raised in homes with parental substance use Exploratory qualitative study using semi-structured interviews; thematic analysis applied Service users’ firsthand experiences; implications for health professionals Parental substance use led to adverse childhood experiences and traumatic events
Four themes emerged: impact on children, school influences, aggravating traumatic experiences, and rebuilding life
Early intervention and trauma-informed care are essential to support affected individuals
Mark TL, Dolan M, Allaire B, et al.; 2024; Florida and Kentucky, USA Untreated Psychiatric and Substance Use Disorders Among Caregivers with Children Reported to Child Protective Services Caregivers with Medicaid coverage whose children were referred to CPS To determine whether caregivers with MH/SUD whose children were referred to CPS received Medicaid-funded MH or SUD treatment Design: case-control study The study focuses on caregivers (service users) with MH/SUD conditions whose children are involved with CPS, highlighting their access to treatment services MH/SUD diagnoses prevalence: 59% of caregivers referred to CPS had MH/SUD; 33% in the control group had MH/SUD (P<0.001)
Age- and sex-matched Medicaid beneficiaries without children referred to CPS (control group) Data sources: linked Medicaid and child welfare records from 2017 to 2020 Treatment receipt among diagnosed caregivers: psychiatric disorders: 38% received counseling; 67% received medication. SUD: 40% received counseling; 38% received medication
Participants: caregivers identified in child welfare records linked to their Medicaid records
Analysis: examined Medicaid claims for MH/SUD diagnoses and receipt of counseling or medications
Martwick J, Kaufmann J, Bailey S, et al.; 2024; USA Impact of Healthcare Location Concordance on Receipt of Preventive Care Among Children Whose Parents Have a Substance Use and/or Mental Health Diagnosis 41,413 parents with at least one SU and/or MH (SU/MH) diagnosis To determine if children of parents with SU/MH diagnoses receive more preventive care—specifically WCCs and vaccinations—when they attend the same clinic as their parents A retrospective cohort study using electronic health record data from the OCHIN network of community health organizations collected between 2010 and 2018 Service user perspective (focus on patients) For children under 15 months, attending the same clinic as their parent is associated with higher rates of WCCs (aRR =1.06; 95% CI: 1.02–1.10) and increased odds of complete vaccinations by age 2 years (aOR =1.12; 95% CI: 1.03–1.21). For children aged 3 to 17 years, there is no significant difference in WCC rates based on clinic concordance. For adolescents up to age 18 years, attending the same clinic as their parent is linked to lower odds of vaccine completion (aOR =0.88; 95% CI: 0.81–0.95). Thus, parent-child clinic concordance improves preventive care for young children but not for older ones, highlighting the importance of family-oriented healthcare for young children of parents with substance use or MH diagnoses
Linked to 65,417 children aged 0 to 17 years who had at least one visit to an OCHIN clinic between 2010 and 2018
Matson PA, Bakhai N, Solomon BS, et al.; 2022; Baltimore, Maryland, USA Understanding caregiver acceptance of screening for family substance use in pediatric clinics serving economically disadvantaged children Adult caregivers (n=271) of pediatric patients at two urban pediatric outpatient clinics in economically disadvantaged neighborhoods To examine caregiver acceptance of pediatricians screening for family/household substance use during well-child visits Cross-sectional study Service user perspective: focused on caregivers’ views regarding substance use screening by pediatricians Caregivers in economically disadvantaged settings support universal screening for substance use in the family/household during pediatric visits
To assess the prevalence of family/household substance use Anonymous computer-based surveys administered to adult caregivers during clinic visits Pediatricians play a crucial role and are trusted professionals who can extend their care by assessing family substance use to enhance child health outcomes
To evaluate the association between family/household substance use and trust in their child’s pediatrician
Matsuda Y, Kim YJ, Salani DA, et al.; 2019; Miami, USA Predictors of Parenting Self-Agency among Mothers Receiving Substance Abuse or Mental Health Treatment 172 mothers receiving outpatient treatment for substance use or MH disorders To explore predictors of parenting self-agency among mothers impacted by MH or SUD Secondary analysis of baseline data from a randomized trial Focused on the experiences of mothers (service users) receiving treatment Increased children’s externalizing problems and higher intensity of daily hassles predicted lower parenting self-agency in mothers
Mothers had at least monthly contact with at least one child under 18 years old Used multivariate linear regression to identify predictors of parenting self-agency Implications for health professionals (nurses) to assist these mothers in improving parenting self-agency Greater family cohesion predicted higher parenting self-agency
Data collected via interviews in participants’ preferred language using an electronic platform Concluded that treatments should address the family unit to enhance mothers’ confidence and effectiveness in parenting
Mechling B, Ahern N, Palumbo R; 2024; USA (University of North Carolina Wilmington) Parental Substance Use Disorder and the Rise in Children Being Raised by Grandparents: Focusing on Children’s Needs and Improving Outcomes Children being raised by grandparents due to parental SUD To explore the experiences, needs, and resources for supporting children raised by grandparents because of parental SUD Literature review of existing studies and data on grandparent-headed households due to parental SUD Service user perspective: examines the challenges and needs of children and grandparents in grandparent-headed households Increasing number of children are being raised by grandparents due to parental SUD
Grandparents who have assumed custodial care of their grandchildren To discuss best practices for healthcare professionals, especially nurses, in supporting this vulnerable population Analysis of research focusing on both grandparents’ and grandchildren’s experiences and outcomes Health professional perspective: highlights the crucial role of nurses and healthcare professionals in recognizing and addressing the unique needs of these families These children face higher risks of psychological and developmental issues due to multiple adverse childhood experiences
To identify future research directions focusing on the children’s needs and improving outcomes Healthcare professionals should support these families to improve children’s outcomes
Meinhofer A, Chandra N, Byanova D, et al.; 2024; USA (nationwide Medicaid data) Foster Care and Health in Medicaid-Enrolled Children Experiencing Parental Opioid Use Disorder Medicaid-enrolled children aged 4 to 18 years who were exposed to POUD between 2014 and 2020 To examine the health and health care outcomes of children experiencing POUD, comparing those with and without foster care involvement Design: population-based cohort study Service users: focus on the health outcomes of children affected by POUD and foster care involvement Foster care involvement among children with POUD increased significantly between 2014 and 2020
Data source: nationwide Medicaid claims data from January 1, 2014, to December 31, 2020 Health professionals: highlights the role of healthcare providers and policymakers in supporting these vulnerable populations Foster children had higher rates of developmental delays, MH issues, and SUD compared to those not in foster care
Analysis: used statistical tests (Pearson χ², t-test, linear regression) and an event study design to compare health outcomes and health care utilization between children with and without foster care involvement They used more health care services, especially in the first year of foster care entry
The study emphasizes the need for supportive policies for affected children and families
Nurjannah N, Oktari RS, Nisa H, et al.; 2024; Banda Aceh, Indonesia Urban children at risk of violence: A qualitative study of experiences of parents, teachers, and service providers of collaborative support Parents:10 parents of abused or at-risk children aided by the Integrated Service Center To understand the perceptions and experiences of parents, teachers, and service providers regarding collaborative support for children at risk of violence Conducted 24 structured interviews Included perspectives from both service users (parents) and health professionals/service providers (counselors, psychologists, paralegals, social workers), as well as teachers Referral sources: parents mainly discovered support services through referrals or recommendations
Service providers: 10 professionals (counselors, psychologists, paralegals, social workers) Utilized a thematic analysis approach for systematic coding and identification of key themes Stigma concerns: fear of stigma, especially in sexual abuse cases, made parents avoid involving teachers
Teachers: 4 teachers familiar with the children Lack of collaboration: schools rarely worked with external agencies, leading to isolated care systems
Communication barriers: reluctance among parents and service providers to engage with teachers hindered support
Policy recommendations: clear policies are needed to promote cross-institutional collaboration and shared responsibilities
Palumbo R, Mechling BM, Ahern NR; 2022; Southeastern North Carolina, USA Parental Opioid Use Disorder: Examining Their Children’s Experiences, Needs, and Road to Resilience Nine children aged 12–17 years in custody of social services who have experienced a parent with OUD To better understand the experiences and needs of youth who have lived with a parent with OUD Qualitative, descriptive study as part of a larger mixed-methods intervention Focused on the children’s (service users) perspectives regarding their experiences and needs Meaning of a parent: children’s experiences with their parents who have OUD
To gain insight into these children’s perceptions to develop targeted interventions that promote resilience Utilized SAMHSA’s Children’s Program Kit: Supportive Education for Children of Addicted Parents Highlighted the role of MH nurses (health professionals) in supporting these children through intervention development and implementation Others involved: impact of extended family, social workers, and peers
Conducted thematic analysis of participants’ verbal responses, behaviors, observations, field notes, and retained materials over eight sessions Witnessing the cycle: observations of parental substance use and its effects
Two sub-themes: ways to cope: children’s coping strategies; support from various sources: role of support systems
Ramstedt M, Raninen J, Larm P, et al.; 2022; Sweden Children with problem drinking parents in Sweden: Prevalence and risk of adverse consequences in a national cohort born in 2001 Nationally representative sample of Swedish youth aged 15–16 years (born in 2001) To estimate how many children in Sweden have problem drinking parents Conducted a survey in 2017 using the Children of Alcoholics Screening Test (CAST-6) Service user perspective: focused on the experiences and well-being of adolescents with problem drinking parents Prevalence: 13.1% had at least one problem drinking parent, higher among girls (15.4%) than boys (10.8%)
Total participants: 5,576 adolescents To assess the risk of poor health, social relationships, and school issues among these children compared to others Measured health status, social relations, and school situation with established instruments Health risks: increased risk of poor general health and psychosomatic issues (RR =1.2–1.9); more likely to use medication for depression, anxiety, and sleep difficulties (RR =2.2–2.6)
Calculated RR to compare outcomes between groups Social relations: worse relationships with parents, especially fathers (RR =3.1)
School situation: more problems at school, including lower satisfaction and increased truancy (RR =2.6)
Ward B, Kippen R, Reupert A, et al.; 2021; Australia Parent and child co-resident status among an Australian community-based sample of methamphetamine smokers A community-based sample of 744 individuals in Victoria, Australia, who primarily smoke methamphetamine To describe the characteristics of parents who primarily smoke methamphetamine and examine their children’s residential status Baseline data from the ‘VMAX’ prospective study Service user perspective focusing on parents who use methamphetamine 53% (394 out of 744) of participants were parents
To investigate differences in socio-demographic, psychosocial, MH, and substance use characteristics based on parental status, gender, and children’s co-residential status Participants recruited via convenience, respondent-driven, and snowball sampling methods 76% of these parents (88% of fathers and 57% of mothers) had no co-resident children
Used univariable and multivariable logistic regression analyses Parents with co-resident children were more likely to have a higher income
Fathers with co-resident children were more likely to be partnered and not have experienced recent violence
Mothers with co-resident children were less likely to have been homeless recently or to have accessed treatment for methamphetamine use
Highlighted the need for accessible support and services for parents who use methamphetamine, regardless of their children’s co-residency status

aOR, adjusted odds ratio; aRR, adjusted RR; CI, confidence interval; CPS, Child Protective Services; EFT, emotion-focused therapy; MH, mental health; OCHIN, Oregon Community Health Information Network; OUD, opioid use disorder; POUD, parental opioid use disorder; PTSD, post-traumatic stress disorder; RR, relative risk; SAMHSA, Substance Abuse and Mental Health Services Administration; SU, substance use; SUD, substance use disorder; WCCs, well-child checks.

Stage 5: collating and summarizing results

The process of collating and summarizing results focused on formulating answers to our research questions. This led to the material presented below in the “Results” section.

Stage 6: consultation exercise (optional stage)

Alongside the five stages of our review, we initiated a consultative process with a diverse group of stakeholders’ child mental health nurses, representatives from support organizations, and professionals who have direct experience with mental health and substance use disorders using a combination of face-to-face sessions, virtual meetings, and email exchanges. This inclusive approach was vital in identifying ongoing challenges and gathering comprehensive insights into children’s experiences, alongside the perspectives of their parents and the professionals who support them. Our collaboration illuminated areas in need of further exploration and ensured that the review addressed the broad spectrum of needs and realities faced by everyone involved.

Following Arksey and O’Malley’s framework (13), this consultative phase served as the final step in our comprehensive review process. Through monthly in-person meetings and supplemental email exchanges, we refined our research questions, aligned the findings with real-world challenges, and ensured that the proposed interventions would be culturally relevant and practically feasible. Building on these varied insights, we then proceeded to sequentially present and discuss the compiled material in the subsequent sections.


Results

The results of this review highlight the multifaceted challenges faced by children of parents with mental health and substance use disorders, emphasizing their increased vulnerability to emotional, social, and developmental risks. Drawing from the literature, the findings underscore the importance of targeted interventions, family engagement, integrated support systems, and continuous monitoring to address these challenges effectively. Each theme is supported by evidence from the reviewed studies, providing a comprehensive understanding of the strategies needed to improve outcomes for these children and their families.

This review highlights significant challenges and risk factors faced by children of parents with mental health and substance use disorders, emphasizing the need for targeted interventions and integrated support systems. We ensured that all statements in the “Results” section are directly supported by cited sources, providing clear evidence for each conclusion drawn.

Impact and risk factors

The impacts of parental substance use and mental health disorders on children include a range of emotional, social, and developmental challenges. Research consistently shows that children exposed to these conditions are at increased risk of maltreatment and behavioral issues that can persist into adulthood, highlighting the profound influence parental health has on child development. A lack of stability and predictability in these environments undermines healthy emotional growth. Parental disorders often hinder the ability to provide consistent, nurturing care, which is vital for secure attachment and emotional regulation (17,18).

Developmentally, children in such environments frequently show delayed milestones in cognitive and emotional growth. Chaotic household conditions linked to substance misuse can impair cognitive abilities and lead to emotional dysregulation (19-21). Additionally, attachment disorders are common, hindering these children from forming secure relationships later in life. Behaviorally, children of parents with mental health and substance use disorders often exhibit externalizing problems, like aggression, and internalizing issues, such as anxiety. Matsuda et al. [2019] describe these behaviors as coping mechanisms developed in the absence of adequate parental guidance, which can have long-term negative effects on social interactions and academic performance (17). Stigma around these disorders often results in social isolation, adding to children’s emotional struggles. Without supportive social networks, they lack the community connections needed for healthy development and resilience.

A major consequence of these environments is the heightened risk of maltreatment, including neglect and abuse (21). A reviewed study emphasizes the importance of family therapy in involving parents to improve family dynamics and reduce risks. Evidence suggests that family therapy can educate parents about the impact of their behavior on their children and provide strategies to manage these challenges effectively. Community-based programs play a critical role in offering support, reducing stigma, and fostering understanding of mental health and substance use disorders. They provide essential social networks and opportunities for positive interactions, crucial for child development and well-being. In summary, children of parents with mental health and substance use disorders face significant challenges, including developmental delays, behavioral issues, and maltreatment (19,22). Targeted interventions and community support can mitigate risks and improve developmental outcomes, allowing these vulnerable children to achieve better health and lead more fulfilling lives (23).

Parent and family engagement

The participation of parents in therapy can foster a healing environment, not just for the individual but for the entire family unit. This approach allows parents to develop better coping strategies, improve parenting skills, and strengthen family dynamics, which are essential for creating a supportive home environment (18,24,25).

Strategies that enhance parental skills often focus on improving communication, conflict resolution, and emotional management. For instance, Mechling et al. [2024] discuss how interventions that include parents, particularly those with substance use disorders, can benefit the entire family system, especially when grandparents are actively involved in raising grandchildren. This involvement can provide additional stability and support, helping to buffer the adverse effects often experienced by children in these households (26).

Furthermore, Matsuda et al. [2019] emphasize the importance of increasing ‘parenting self-agency’, or parents’ belief in their ability to perform parenting roles effectively as a critical factor in improving child outcomes. Training programs that empower parents with skills and knowledge about child development and effective parenting strategies can lead to more competent parenting, which in turn supports children’s emotional and psychological well-being (17).

Extended family members, such as grandparents, often play a pivotal role in providing care and stability. Research by Mechling et al. [2024] highlights how grandparents often step into primary caregiving roles when parents struggle with addiction or mental health issues. This shift not only affects the grandparents’ lives but also has significant implications for the emotional and developmental trajectory of children. These dynamics underscore the importance of including extended family members in therapeutic interventions, which can enhance the resilience of the entire family network (26).

Moreover, involving parents in therapeutic processes also means addressing their mental health needs, which can significantly affect their parenting. For example, Guastaferro et al. [2021] found that treating parental mental health issues could lead to improved parenting practices and better child outcomes (27). Similarly, interventions like those discussed by Champion et al. [2023] which aim to educate parents about health behaviors and provide strategies for managing their health, can have a profound impact on the overall health and well-being of the family (18). Additionally, educational programs that involve parents, as reported by Guastaferro et al. [2021] can align parent and child perceptions on parenting practices, which is crucial for effective communication and relationship building (27). Understanding and managing parental expectations and behaviors can help mitigate potential conflicts and misunderstandings within the family, leading to a more harmonious home environment and better mental health outcomes for children.

Community and school-based programs also play a crucial role in supporting families dealing with parental substance use and mental health disorders. As noted by Guastaferro et al. [2021] integrating school-based support with family therapy can provide children with a consistent support network that extends beyond the home, promoting resilience and stability (27). In summary, involving parents and extended family members in therapeutic interventions not only addresses the immediate challenges associated with parental mental health and substance use disorders but also enhances the long-term resilience and well-being of children. By fostering an environment of understanding, support, and continuous learning, these interventions can significantly improve the life trajectories of all family members involved.

Integrated support systems

Children of parents with mental health and substance use disorders face an elevated risk of emotional and behavioral challenges, often due to the instability these conditions bring to the home. Studies highlight increased risks of child maltreatment associated with parental mental health issues (21), and untreated parental disorders frequently result in child protective services’ involvement (6). Interventions like psychotherapy can mitigate these risks by improving parenting practices and stabilizing home environments (21,28).

Based on the review of the included articles, proactive and comprehensive intervention strategies are consistently highlighted as essential for addressing root causes rather than simply reacting to crises. Effective support systems that integrate mental health care, substance abuse treatment, primary healthcare, and social services are widely recommended in the literature for providing holistic support to both parents and children (21,28). Such coordinated approaches not only aid in treating immediate conditions but are also noted to prevent the recurrence of issues related to mental health and substance use (6).

The reviewed studies emphasize the importance of strong policy frameworks to support these integrated care models by ensuring adequate funding, resources, and training for service delivery. Additionally, several articles suggest that policies aimed at reducing stigma surrounding mental health and substance use disorders play a critical role in encouraging families to seek timely help (7,29). Early intervention and preventive measures are frequently identified as key components of effective systems, enabling the identification of at-risk families before problems escalate. Research points to the value of equipping parents with skills and support to foster healthy family dynamics, which directly benefits their children’s emotional and psychological well-being (6,7,30).

Findings indicate that options such as family therapy, individual counseling, and specialized child support are effective in helping children manage the challenges associated with their parents’ mental health and substance use disorders (21,28). Research underscores the necessity of continuous monitoring and evaluation within integrated systems to ensure interventions remain responsive to families’ evolving needs (6). Evidence also suggests that regular feedback from healthcare providers, social workers, and families contributes to refining practices and improving outcomes (25). Research from Lopes et al. [2021] and Mark et al. [2024] offers valuable insights, guiding the way to more effective, innovative support models for vulnerable children and their families. Implementing these systems through robust policy frameworks can make essential services more accessible, reducing the enduring impacts on children’s wellbeing (6,21).

Continuous monitoring and adaptive support

Children of parents with mental health and substance use disorders face considerable emotional, social, and developmental challenges due to instability at home. Educational and community programs offer critical support, helping children build resilience and stability in otherwise unpredictable environments. Schools provide structure, emotional support, and coping strategies through counseling and support programs, often becoming a crucial resource for children who may not have access to mental health services. Educators and school staff, who frequently notice behavioral shifts early, play a key role in initiating timely interventions, addressing issues before they escalate (31,32). Community programs further bolster this support, offering safe spaces for children to develop social skills, resilience, and self-esteem. Through mentorship, support groups, and recreational activities, community centers foster a sense of belonging and provide mental health resources, crucial in areas with high substance use rates (24,25).

Integrating healthcare services within these frameworks ensures that children’s physical and emotional needs are consistently met, creating a foundation for healthy development. For instance, regular health screenings help in early identification of issues, especially for children at risk of neglect, allowing timely intervention and continuous support. Programs that support positive parent-child interactions in therapeutic settings strengthen family relationships, reducing neglect and improving family cohesion (25,27). Research underscores the long-term impact of stable support systems, linking them to better educational and health outcomes for children. By addressing immediate needs, these programs can disrupt cycles of neglect and abuse, improving social and economic outcomes in adulthood (31,32). Thus, investing in integrated support systems is essential for creating resilience and stability for these vulnerable children (25,27,33). Continuous monitoring and adaptive support are also essential to meet the evolving needs of children as they progress through developmental stages. Early in life, children may require counseling for emotional distress, while later, they might benefit more from academic mentoring or peer support groups to address broader social challenges (34). Pediatric clinics in underserved communities often serve as key touchpoints for ongoing assessment, allowing providers to observe shifts in emotional and social needs and respond with appropriate interventions (35).

This adaptive support requires collaboration among educators, healthcare providers, and social workers to ensure that all aspects of a child’s well-being are addressed. Regular, culturally sensitive assessments enable personalized support that aligns with each child’s situation. However, implementing continuous monitoring systems faces challenges, including limited resources and institutional resistance. Overcoming these barriers requires leadership committed to child-centered approaches. Evidence from studies, like Palumbo et al. [2022], supports the impact of such systems, showing that tailored interventions can significantly enhance resilience and emotional regulation in children of parents with substance use disorders (34). In summary, adaptive support systems, combined with educational and community resources, are vital to supporting children of parents with mental health and substance use challenges. Investing in responsive, comprehensive frameworks helps nurture resilience and improve long-term well-being, offering these children a pathway to a healthier, more stable future (22).


Discussion

The discussion integrates the four primary themes identified through the review: impact and risk factors, parent and family engagement, integrated support systems, and continuous monitoring and adaptive support. Each theme offers insight into the complex challenges faced by children of parents with mental health and substance use disorders and highlights opportunities for effective interventions. By exploring these themes in an integrated manner, we can better understand how interventions can be optimized to support these vulnerable children.

Impact and risk factors

Children in environments affected by parental mental health and substance use disorders face significant instability that can lead to emotional, social, and developmental setbacks. The literature consistently shows a direct correlation between parental health issues and increased risk for child maltreatment, neglect, and behavioral problems (30,36). These children often experience an unstable home environment marked by inconsistent caregiving (17). For instance, studies have highlighted how children in these settings may develop internalizing behaviors such as anxiety and depression or externalizing behaviors such as aggression and conduct problems (30,36,37). This dual spectrum of behavioral issues underscores the need for interventions that address both the emotional and behavioral health of the child. Furthermore, the unpredictability and inconsistency of the home environment can hinder secure attachment, which is critical for healthy emotional development. Secure attachment is fundamental for children’s ability to regulate emotions and develop resilience in the face of adversity (23).

Effective interventions must thus focus on stabilizing these environments and providing consistent, trauma-informed support to mitigate these risks (21). Trauma-informed care, which emphasizes understanding, recognizing, and responding to the effects of trauma, can help create a safe and supportive environment that is conducive to positive developmental outcomes (38). Additionally, programs aimed at supporting parents in managing their mental health and substance use are crucial, as improving parental well-being directly impacts the child’s environment (6).

Parent and family engagement

Engaging parents in therapeutic processes and enhancing their parenting skills are crucial for the emotional and psychological well-being of the child (27,39). Interventions need to be tailored to improve family dynamics and support structures within the home, with special consideration for the roles extended family members, such as grandparents, play in providing stability (15). For instance, when grandparents step in as primary caregivers, they can provide a sense of stability and continuity that is often missing in homes affected by mental health and substance use issues (36). Parental engagement in therapy helps improve communication within the family, enhances emotional availability, and ultimately fosters a more supportive home environment (17,27). Strategies that enhance parental skills often focus on improving communication, conflict resolution, and emotional regulation, which are critical for maintaining a nurturing environment. Research indicates that involving parents in interventions, even those struggling with their own health challenges, can create a more positive family atmosphere that benefits children significantly (30). The inclusion of extended family in support systems is particularly valuable. Grandparents and other relatives often take on caregiving roles, and their involvement can help buffer the adverse effects experienced by children in these settings (15). Involving the wider family network in therapeutic interventions not only provides additional support for the child but also alleviates some of the caregiving burden on parents, thus reducing stress within the family unit.

Integrated support systems

Addressing the comprehensive needs of these families requires integrated systems that coordinate healthcare, education, and community services. Such systems should aim to provide seamless support, addressing both medical and psychosocial needs to prevent the worsening of issues and improve overall family functioning (6,21). Integrated support systems that bring together healthcare providers, social services, and educational institutions can effectively address the multifaceted needs of these children and their families (38). For example, healthcare professionals can work with schools to ensure that children receive the necessary emotional and academic support. School-based programs that focus on social-emotional learning have been shown to improve resilience and coping skills in children facing adverse home environments (32). By integrating healthcare and educational resources, children can receive holistic support that addresses both their mental health needs and their academic challenges.

Moreover, the integration of healthcare and social services is crucial for ensuring that families receive comprehensive care without falling through the cracks of fragmented service delivery (31). Families dealing with mental health and substance use issues often require a range of services, from mental health counseling to financial assistance, and integrated support systems can help streamline access to these resources. Such systems not only reduce the burden on families but also enhance the effectiveness of interventions by ensuring that all aspects of a family’s needs are addressed in a coordinated manner.

Continuous monitoring and adaptive support

Children of parents with mental health and substance use disorders benefit from ongoing support that adapts to their evolving needs (34). Educational and community programs play a vital role in providing stability and resources necessary for building resilience and coping skills. Schools provide a stable environment where children can access counseling services, support groups, and other resources that help them manage the challenges they face at home (31). Continuous monitoring is essential for adapting interventions to meet the changing needs of children as they grow. The developmental stage of each child must be considered, as the needs of a 10-year-old differ significantly from those of an adolescent nearing adulthood (32). Adaptive support requires collaboration among educators, healthcare providers, and social workers to ensure that all aspects of a child’s well-being are addressed. For instance, regular assessments of a child’s emotional and social needs can help identify emerging issues early, allowing for timely intervention (34). Community programs also provide crucial support by offering safe spaces where children can engage in positive social interactions and develop important life skills. Programs such as mentorship, recreational activities, and support groups can foster a sense of belonging and community, which is often lacking for children in these situations (31). Such community-based initiatives can be particularly effective in areas with limited access to formal mental health services, as they provide a more accessible form of support for children and their families.

Cross-theme discussion

These themes are not isolated; rather, they intersect to highlight the complexity of supporting children in these circumstances. For instance, integrated support systems facilitate continuous monitoring and adaptive support, which in turn can enhance parent and family engagement. Addressing the immediate impact and risk factors can lay the groundwork for long-term stability through integrated and continuous support mechanisms. The dynamic interplay between these themes highlights the need for a multi-level approach that addresses both the immediate and long-term needs of these children (39). The integration of support systems, as seen in successful interventions, demonstrates the value of a holistic approach that brings together different sectors to support both the child and the family. For example, programs that combine family therapy with school-based support have shown improved outcomes in both academic performance and emotional well-being (21). This cross-sector collaboration ensures that children receive consistent support across different areas of their lives, reducing the likelihood of issues being overlooked or inadequately addressed.

The discussion integrates findings from the literature, illustrating how interventions have succeeded or failed in various contexts. For instance, resilience-building programs that include parental involvement have shown promise in mitigating the negative impacts of parental substance use (39). Programs that focus on building emotional regulation skills in children, while simultaneously addressing the mental health needs of the parent, have been particularly effective in reducing behavioral problems and improving overall family functioning (30). Gender-sensitive approaches are also critical, as boys and girls often experience and respond to parental mental health and substance use issues differently (30). Boys may exhibit more externalizing behaviors, such as aggression, while girls are more likely to internalize their distress, leading to anxiety and depression. Tailoring interventions to address these gender-specific needs can enhance their effectiveness, as it ensures that the unique experiences of each child are considered (36).

Contribution to research science

This review contributes to the research science by clarifying the complex interplay of factors affecting children of parents with mental health and substance use disorders. It identifies gaps in current research, particularly the lack of targeted, child-specific interventions and the need for integrated approaches that consider the child’s perspective within family and community contexts. The review also underscores the importance of resilience-building as a critical component of interventions and highlights the need for more gender-sensitive approaches that recognize the distinct needs of boys and girls.

By synthesizing existing literature, this review provides a foundation for future research and intervention development. It emphasizes the need for comprehensive, multi-level approaches that integrate healthcare, education, and community resources to support these children effectively. Furthermore, it calls for more longitudinal studies that can provide insights into the long-term effectiveness of different interventions and help identify the most promising strategies for supporting these vulnerable populations.


Limitations

This scoping review has several limitations that should be acknowledged. First, the search was limited to peer-reviewed academic journals, potentially excluding relevant grey literature, such as reports from non-governmental organizations or policy documents, which could provide additional insights into support mechanisms and intervention strategies for children of parents with mental health and substance use disorders. Second, the review only included studies published in English, which may have excluded important findings from non-English literature, potentially introducing a language bias. Third, the scope was broad, which while providing a comprehensive overview, might have limited the depth of analysis in specific areas, such as cultural influences on resilience or gender-specific challenges. Furthermore, the review primarily focused on children aged 10–18 years, potentially overlooking the unique needs of younger children who might require different types of support. Lastly, as a scoping review, this study did not evaluate the quality of included studies, limiting the ability to draw conclusions regarding the efficacy of the interventions discussed. Future research would benefit from systematic reviews or meta-analyses to assess the effectiveness of specific interventions for this vulnerable population.


Conclusions

This scoping review emphasizes the critical need for comprehensive, tailored interventions to address the diverse and complex challenges faced by children of parents with mental health and substance use disorders. These children encounter substantial risks, including emotional, psychological, and developmental hurdles, often exacerbated by unstable home environments and inadequate support systems. Effective interventions must adopt a multi-level approach that integrates healthcare, education, and community services to ensure cohesive, targeted support.

Structured programs focused on resilience and emotional regulation are essential. Such interventions could provide children with coping mechanisms to manage stress and trauma, enhancing their capacity to navigate challenging home situations. Involving parents and extended family members in therapeutic processes can significantly improve family dynamics. Programs that support parental skill development in communication, conflict resolution, and emotional regulation foster a more supportive environment. This is especially beneficial when extended family members, like grandparents, play a caregiving role.

Developing integrated support systems that bridge healthcare, mental health, and social services is crucial. These systems should address both the medical and psychosocial needs of children and parents to prevent fragmented care and improve access to resources. Policymakers must prioritize funding and resources to support such integrative models. Schools and community programs should offer ongoing support that adapts to children’s evolving needs, providing a stable foundation for their development. Continuous assessment of children’s emotional and social needs, facilitated by collaboration among educators, healthcare providers, and social workers, ensures timely interventions that can adjust to developmental stages.

Future research should aim to evaluate the effectiveness of these interventions, explore gender-sensitive approaches, and develop culturally relevant strategies. Investing in integrated, adaptive support systems can significantly improve the long-term well-being and life outcomes of these vulnerable children, offering them a pathway toward a more stable and healthy future.

We have proposed recommendations to practitioners and policymakers for implementing solutions tailored to the target groups (Table 2).

Table 2

Evidence-based programs supporting children of parents with mental health and substance use disorders

Program name Target audience Description Key outcomes Source
SAMHSA’s Children’s Program Kit Children of parents with substance use disorders A program providing supportive education for children of addicted parents to promote resilience Improved emotional regulation, coping strategies, and peer support Palumbo et al. 2022
Emotion-focused therapy (EFT) Parents with mental health issues A psychotherapy approach targeting emotional awareness and interpersonal challenges in families Reduces aggressive behaviors, improves family dynamics, and decreased child maltreatment risk Lopes et al. 2021
Incredible years Parents of children (ages 3–12 years) A parent training and school-based program focusing on strengthening parenting skills and child resilience Enhanced parenting practices, reduced behavioral problems in children Guastaferro et al. 2021
Triple P—positive parenting program Parents of children across age groups Multi-level intervention offering parenting strategies for different developmental stages Reduced child behavioral issues, improved parental mental health Champion et al. 2023
Safe care Families at risk of child maltreatment Home-based training program focused on parent-child interaction, child safety, and health Decreased maltreatment reports and enhanced caregiving environments Guastaferro et al. 2021
Family talk intervention Families with parental mental illness Psychoeducation for families to foster open communication and understanding of mental illness Increased resilience and reduced stigma among children Ward et al. 2021
Project safe Children exposed to trauma A group-based intervention focusing on trauma informed care and emotional healing Improved mental health outcomes and emotional resilience Maina et al. 2021
Parent child assistance program (PCAP) Pregnant or parenting mothers with substance use disorders Long-term home visitation program addressing substance use recovery and parenting Reduced maternal substance use and improved child development outcomes Dyba et al. 2019

Acknowledgments

None.


Footnote

Reporting Checklist: The authors have completed the PRISMA-ScR reporting checklist. Available at https://jhmhp.amegroups.com/article/view/10.21037/jhmhp-24-131/rc

Peer Review File: Available at https://jhmhp.amegroups.com/article/view/10.21037/jhmhp-24-131/prf

Funding: None.

Conflicts of Interest: All authors have completed the ICMJE uniform disclosure form (available at https://jhmhp.amegroups.com/article/view/10.21037/jhmhp-24-131/coif). The authors have no conflicts of interest to declare.

Ethical Statement: The authors are accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved.

Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0/.


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doi: 10.21037/jhmhp-24-131
Cite this article as: Jørgensen K, Frederiksen J, Hansen M, Dubovcová M. Challenges and support for children of parents with mental health and substance use disorders: a scoping review. J Hosp Manag Health Policy 2025;9:21.

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